Donata Vercelli, MD

Professor, Cellular and Molecular Medicine

Director, Molecular Genomics- A2DRC

Director, Arizona Center for the Biology of Complex Diseases

Professor, BIO5 Institute

(520) 626-6387

donata@email.arizona.edu

Research Interest:

Genetic, epigenetic and environmental mechanisms that control susceptibility to complex lung diseases.

Publications

DeVries, Avery, et al. “Maternal Prenatal Immunity, Neonatal Trained Immunity, and Early Airway Microbiota Shape Childhood Asthma Development”. Allergy, vol. 77, no. 12, Dec. 2022, pp. 3617–3628.

Pivniouk, Vadim, et al. “Airway Administration of {OM-85}, a Bacterial Lysate, Blocks Experimental Asthma by Targeting Dendritic Cells and the {epithelium IL-33 ILC2} Axis”. J. Allergy Clin. Immunol., vol. 149, no. 3, Mar. 2022, pp. 943–956.

Pivniouk, Vadim, et al. “The {OM-85} Bacterial Lysate Inhibits {SARS-CoV-2} Infection of Epithelial Cells by Downregulating {SARS-CoV-2} Receptor Expression”. J. Allergy Clin. Immunol., vol. 149, no. 3, Mar. 2022, pp. 923–933.e6.

Vercelli, Donata. “Microbiota and Human Allergic Diseases: The Company We Keep”. Curr. Opin. Immunol., vol. 72, Oct. 2021, pp. 215–220.

Lynch, Susan V, and Donata Vercelli. “Microbiota, Epigenetics, and Trained Immunity. Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood”. Am. J. Respir. Crit. Care Med., vol. 203, no. 7, Apr. 2021, pp. 802–808.

Morin, Andréanne, et al. “Epigenetic Landscape Links Upper Airway Microbiota in Infancy With Allergic Rhinitis at 6 Years of Age”. J. Allergy Clin. Immunol., vol. 146, no. 6, Dec. 2020, pp. 1358–1366.

Kimura, Hiroki, et al. “Type 2 Inflammation Modulates {ACE2} and {TMPRSS2} in Airway Epithelial Cells”. J. Allergy Clin. Immunol., vol. 146, no. 1, July 2020, pp. 80–88.e8.

Giammò, Alessandro, et al. “Urethral Bulking With Bulkamid: An Analysis of Efficacy, Safety Profile, and Predictors of Functional Outcomes in a Single-Center Cohort”. Neurourol. Urodyn., vol. 39, no. 5, June 2020, pp. 1523–1528.

Pivniouk, Vadim, et al. “The Role of Innate Immunity in Asthma Development and Protection: Lessons from the Environment”. Clin. Exp. Allergy, vol. 50, no. 3, Mar. 2020, pp. 282–290.

DeVries, Avery, et al. “Epigenome-Wide Analysis Links {SMAD3} Methylation at Birth to Asthma in Children of Asthmatic Mothers”. J. Allergy Clin. Immunol., vol. 140, no. 2, Aug. 2017, pp. 534–542.

Carr, Tara F, et al. “Prevalence of Asthma in School Children on the {Arizona-Sonora} Border”. J. Allergy Clin. Immunol. Pract., vol. 5, no. 1, Jan. 2017, pp. 114–120.e2.

Clinical Trials

Study Title (link to more info on this site)	Link to Study	Trial Status	Principal Investigator
BEAMS	view	Current Trial - Enrolling	Paloma Beamer, PhD, Dean Billheimer, PhD, Tara F. Carr, MD, Darren A. Cusanovich, PhD, Fernando Martinez, MD, Donata Vercelli, MD
OM-Pharma	view	Current Trial - Enrolling	Donata Vercelli, MD

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Donata Vercelli, MD

Research Interest:

Publications

Clinical Trials