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Clinical and Population Research

Our Clinical and Population Research aims to determine the effectiveness of medications, devices, diagnostic products, and treatments in the field of respiratory illnesses, food allergies, and allergies. We are at the forefront of clinical trials and strive to turn our findings into treatments that will prevent, treat, and relieve patients suffering from respiratory illnesses. To find out about participating in one of our actively enrolling trials, click here. 

Clinical and Population Trials - Enrolling

Study Title (link to more info on this site) Principal Investigator
A Long-Term Prospective Observational Safety Study of the Incidence of and Risk Factors for Fibrosing Colonopathy in US Patients with Cystic Fibrosis Treated with Pancreatic Enzyme Replacement Therapy: A Harmonized Protocol Across Sponsors Cori L. Daines, MD
B-cell adaptive immune profile in emphysema-predominant COPD
BEAMS Paloma Beamer, PhD, Dean Billheimer, PhD, Tara F. Carr, MD, Darren A. Cusanovich, PhD, Fernando Martinez, MD, Donata Vercelli, MD
CC16 COVID Pilot Stefano Guerra, MD, PhD, MPH
Development of Surfactant Protein A-Derived Peptidomimetics for the Treatment of Asthma Scott Boitano, PhD, Julie Ledford, PhD
Enhanced Single-cell Genomics Tools for Understanding the Temporal Dynamics of Development and Disease (MIRA) Darren A. Cusanovich, PhD
Gossamer: LEDA Eugene R. Bleecker, MD
Microbiome Sputum Study Cori L. Daines, MD
Multi-Center Validation of Predictive Sputum Bio-markers in CF (Utah Sputum Study) Cori L. Daines, MD
OM-Pharma Donata Vercelli, MD
Optimize Pseudomonas Eradication in Children Cori L. Daines, MD
PreCISE (Precise Intervention for Severe and/or Exacerbation-Prone Asthma) Network Study Eugene R. Bleecker, MD
Vertex 611-110 Cori L. Daines, MD

Clinical and Population Trials - Enrollment Complete

Study Title (link to more info on this site) Principal Investigator
Effects of Aerobic Exercise on Asthmatic Responses in Obese Adults Christian Bime, MD, MSC
Gilead Pseudomonas Cori L. Daines, MD
Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness Wayne J. Morgan, MD
Supervised Asthma Medication in Schools (SAMS) Lynn B. Gerald, PhD, MSPH
Vertex 809-105 Cori L. Daines, MD

Clinical and Population Trials - Closed

Study Title (link to more info on this site) Principal Investigator
(ORBEX) Randomized, placebo-controlled, multicenter study to assess the efficacy, safety, and tolerability of Oral Bacterial Extract for the prevention of wheezing lower respiratory tract illness Fernando Martinez, MD, Wayne J. Morgan, MD
AquADEKs2 Cori L. Daines, MD
AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS)
Asthma BMI Baseline Study (ABBS) Lynn B. Gerald, PhD, MSPH
Best African American Response to Asthma Drugs (BARD) Fernando Martinez, MD
CHRONIC REFRACTORY COUGH COHORT STUDY (COCO) Lynn B. Gerald, PhD, MSPH
Cumberland: Aspirin Exacerbation Respiratory Disease (AERD) Tara F. Carr, MD
Gossamer: TITAN Tara F. Carr, MD
IMPACC COVID
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) Lynn B. Gerald, PhD, MSPH
Inhaled Mannitol in CF Cori L. Daines, MD
Innate Immunity in Asthma (U19)
Losartan Effects on Emphysema Progression (LEEP) Lynn B. Gerald, PhD, MSPH
Pilot of Lifestyle and Asthma iNtervention (PLAN) Lynn B. Gerald, PhD, MSPH
Preventing Asthma in High Risk Kids (PARK) Fernando Martinez, MD
Step-Up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS) Fernando Martinez, MD
Steroids in Eosinophil Negative Asthma (SIENA) Fernando Martinez, MD
Trial of Roflumilast in Asthma Management (TRIM) Lynn B. Gerald, PhD, MSPH
Vertex 661-108 Cori L. Daines, MD
Vertex 809-011b Cori L. Daines, MD
Vertex 809-110 Cori L. Daines, MD